Assay Detail
Functional
CHEMBL5320595
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Antitumor activity against human MDA-MB-231 cells assessed as cell growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.26 | 4.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3288599 | — | — | 1 | 4.44 |
| CHEMBL295316 | PLUMBAGIN | 1.0 | 1 | 4.29 |
| CHEMBL3288601 | — | — | 1 | 4.20 |
| CHEMBL43612 | JUGLONE | — | 1 | 4.12 |
| CHEMBL3288598 | — | — | 1 | - |
| CHEMBL3288600 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3288599 | — | IC50 | = | 36100.0 | nM | 4.44 |
| CHEMBL295316 | PLUMBAGIN | IC50 | = | 51100.0 | nM | 4.29 |
| CHEMBL3288601 | — | IC50 | = | 62900.0 | nM | 4.20 |
| CHEMBL43612 | JUGLONE | IC50 | = | 75700.0 | nM | 4.12 |
| CHEMBL3288598 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3288600 | — | IC50 | > | 100000.0 | nM | - |