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Assay Detail

CHEMBL5320602

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against human MCF7 expressing HER-2 cells assessed as cell growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment.
Astrain-Redin N, Sanmartin C, Sharma AK, Plano D.
J Med Chem (2023) 66 : 3703 -3731
PubMed 36858050 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.22 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5407233 1 6.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5407233 IC50 = 600.0 nM 6.22