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Assay Detail

CHEMBL5320901

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Almond beta-glucosidase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Prunus dulcis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis of the Purported Structure of Glyphaeaside C and Proposed Revisions to the Structures of the Glyphaeaside Alkaloids.
Byatt BJ, Kato A, Pyne SG.
J Nat Prod (2023) 86 : 1261 -1273
PubMed 37125736 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.86 6.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5430441 1 6.04
CHEMBL5400940 1 4.82
CHEMBL469844 1 4.40
CHEMBL5401104 1 4.17
CHEMBL2177695 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5430441 IC50 = 920.0 nM 6.04
CHEMBL5400940 IC50 = 15000.0 nM 4.82
CHEMBL469844 IC50 = 40000.0 nM 4.40
CHEMBL5401104 IC50 = 68000.0 nM 4.17
CHEMBL2177695 IC50 = 175000.0 nM -