Assay Detail
Toxicity
CHEMBL5321453
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Cytotoxicity against human HPL1D cells incubated for 24 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | HPL1D |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification, in-vitro anti-plasmodial assessment and docking studies of series of tetrahydrobenzothieno[2,3-d]pyrimidine-acetamide molecular hybrids as potential antimalarial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.49 | 4.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5401736 | — | — | 1 | 4.57 |
| CHEMBL5396997 | — | — | 1 | 4.54 |
| CHEMBL5401652 | — | — | 1 | 4.50 |
| CHEMBL5437832 | — | — | 1 | 4.44 |
| CHEMBL5422826 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5401736 | — | IC50 | = | 27200.0 | nM | 4.57 |
| CHEMBL5396997 | — | IC50 | = | 28700.0 | nM | 4.54 |
| CHEMBL5401652 | — | IC50 | = | 31300.0 | nM | 4.50 |
| CHEMBL5437832 | — | IC50 | = | 36100.0 | nM | 4.44 |
| CHEMBL5422826 | — | IC50 | = | 39900.0 | nM | 4.40 |