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Assay Detail

CHEMBL5321975

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Yellow fever virus 17D infected in Huh-7 cells assessed as reduction in cytopathic effect
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Yellow fever virus
Cell Type Huh-7
Confidence 1 — Organism
Curated By Autocuration

Target

Yellow fever virus (CHEMBL613731)
Type ORGANISM
Organism Yellow fever virus

Publication

Synthesis and evaluation of anti-yellow fever virus activity of new 6-aryl-3-R-amino-1,2,4-triazin-5(4H)-ones.
Novodvorskyi Y, Lesyk R, Komarov I, Lega D, Zhuravel I, Moskalenko O, Sukhoveev V, Demchenko A.
Eur J Med Chem (2023) 248 : 115117 -115117
PubMed 36657300 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.68 6.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5420583 1 6.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5420583 EC50 = 210.0 nM 6.68