Assay Detail
Functional
CHEMBL5322309
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against RXRalpha knockout human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.47 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5438255 | — | — | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5438255 | — | IC50 | = | 3362.0 | nM | 5.47 |