Assay Detail
Functional
CHEMBL5322866
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Antiviral activity against EV-68 US/KY/14-18953 infected in human RD cells assessed as reduction in virus induced cytopathic effect incubated for 3 days by visual analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | enterovirus D68 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, antiviral activity, and computational study of β-d-xylofuranosyl nucleoside phosphonates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.05 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL283403 | ENVIROXIME | 2.0 | 1 | 6.72 |
| CHEMBL5403083 | — | — | 1 | 4.80 |
| CHEMBL5425806 | — | — | 1 | 4.34 |
| CHEMBL5398633 | — | — | 1 | 4.33 |
| CHEMBL5436734 | — | — | 1 | - |
| CHEMBL5433746 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL283403 | ENVIROXIME | EC50 | = | 190.0 | nM | 6.72 |
| CHEMBL5403083 | — | EC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL5425806 | — | EC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL5398633 | — | EC50 | = | 47000.0 | nM | 4.33 |
| CHEMBL5436734 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL5433746 | — | EC50 | > | 100000.0 | nM | - |