Assay Detail
Functional
CHEMBL5322870
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Antiviral activity against MeV CC strain infected in African green monkey Vero 76 cells assessed as reduction in virus induced cytopathic effect incubated for 6 days by visual analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Measles morbillivirus |
| Cell Type | Vero 76 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, antiviral activity, and computational study of β-d-xylofuranosyl nucleoside phosphonates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 4.84 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL374528 | — | — | 1 | 6.16 |
| CHEMBL5403083 | — | — | 1 | 4.92 |
| CHEMBL5436734 | — | — | 1 | 4.14 |
| CHEMBL5433746 | — | — | 1 | 4.14 |
| CHEMBL5425806 | — | — | 1 | - |
| CHEMBL5398633 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL374528 | — | EC50 | = | 700.0 | nM | 6.16 |
| CHEMBL5403083 | — | EC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL5436734 | — | EC50 | = | 72000.0 | nM | 4.14 |
| CHEMBL5433746 | — | EC50 | = | 72000.0 | nM | 4.14 |
| CHEMBL5425806 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL5398633 | — | EC50 | > | 100000.0 | nM | - |