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Assay Detail

CHEMBL5323501

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-2 variant Omicron BA.3 infected in African green monkey Vero E6 cells assessed as reduction in virus titers of progeny virus in supernatant measured after 72 hrs by CPE assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Cell Type Vero E6
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Antiviral Activity of Cannabidiolic Acid and Its Methyl Ester against SARS-CoV-2.
Tamburello M, Salamone S, Anceschi L, Governa P, Brighenti V, Morellini A, Rossini G, Manetti F, Gallinella G, Pollastro F, Pellati F.
J Nat Prod (2023) 86 : 1698 -1707
PubMed 37402317 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.62 4.73

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL499043 1 4.73
CHEMBL498672 CANNABIDIOLIC ACID 2.0 1 4.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL499043 IC50 = 18600.0 nM 4.73
CHEMBL498672 CANNABIDIOLIC ACID IC50 = 31700.0 nM 4.50