Assay Detail
Binding
CHEMBL5325167
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Inhibition of human HDAC1 measured after 1 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Evolution of Slow-Binding Inhibitors Targeting Histone Deacetylase Isoforms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.34 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5440469 | — | — | 1 | 8.70 |
| CHEMBL4293858 | — | — | 1 | 5.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5440469 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL4293858 | — | IC50 | = | 1080.0 | nM | 5.97 |