Assay Detail
Binding
CHEMBL5325631
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-BTX-B from bovine cortex sodium channel assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Tissue | Cortex |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
What We Have Gained from Ibogaine: α3β4 Nicotinic Acetylcholine Receptor Inhibitors as Treatments for Substance Use Disorders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.32 | 8.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1215855 | — | — | 1 | 8.44 |
| CHEMBL5440131 | — | — | 1 | 8.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1215855 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL5440131 | — | Ki | = | 6.4 | nM | 8.19 |