Assay Detail
Functional
CHEMBL5325842
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Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pleiotropic effects of a mitochondrion-targeted glutathione reductase inhibitor on restraining tumor cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.76 | 4.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5425052 | — | — | 1 | 4.76 |
| CHEMBL5403853 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5425052 | — | IC50 | = | 17400.0 | nM | 4.76 |
| CHEMBL5403853 | — | IC50 | > | 100000.0 | nM | - |