Assay Detail
Binding
CHEMBL5325870
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of glutathione reductase (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glutathione reductase, mitochondrial (CHEMBL2755) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Pleiotropic effects of a mitochondrion-targeted glutathione reductase inhibitor on restraining tumor cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.23 | 6.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5425052 | — | — | 1 | 6.23 |
| CHEMBL5403853 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5425052 | — | IC50 | = | 590.0 | nM | 6.23 |
| CHEMBL5403853 | — | IC50 | - | — | - |