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Assay Detail

CHEMBL5326170

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of ARFGAP1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

ADP-ribosylation factor GTPase-activating protein 1 (CHEMBL5465332)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Ras superfamily GTPase activating proteins in cancer: Potential therapeutic targets?
Xiao H, Wang G, Zhao M, Shuai W, Ouyang L, Sun Q.
Eur J Med Chem (2023) 248 : 115104 -115104
PubMed 36641861 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.30 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259181 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259181 EC50 = 500.0 nM 6.30