Assay Detail
Binding
CHEMBL5326392
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum D10 trophozite lysates FP-2 pretreated with compound for 1 hr followed by labeling with Cy5-DCG04 for 1 hr by fluorescence scanning analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Subcellular | Lysates |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Falcipains: Biochemistry, target validation and structure-activity relationship studies of inhibitors as antimalarials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.07 | 8.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL541700 | GALLINAMIDE A | — | 1 | 8.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL541700 | GALLINAMIDE A | IC50 | = | 8.5 | nM | 8.07 |