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Assay Detail

CHEMBL5326408

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of heme (unknown origin) assessed as inhibition of hemozoin formation incubated for 24 hrs by FBIT test
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Not specified
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Target

Heme (CHEMBL4651321)
Type SMALL MOLECULE

Publication

Falcipains: Biochemistry, target validation and structure-activity relationship studies of inhibitors as antimalarials.
Patra J, Rana D, Arora S, Pal M, Mahindroo N.
Eur J Med Chem (2023) 252 : 115299 -115299
PubMed 36996716 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.58 6.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4215216 1 6.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4215216 IC50 = 260.0 nM 6.58