Assay Detail
Functional
CHEMBL5326421
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Antiplasmodial activity against Plasmodium falciparum W2
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Falcipains: Biochemistry, target validation and structure-activity relationship studies of inhibitors as antimalarials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.85 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5420328 | — | — | 1 | 9.70 |
| CHEMBL5411543 | — | — | 1 | 9.35 |
| CHEMBL5407224 | — | — | 1 | 9.09 |
| CHEMBL486232 | — | — | 1 | 8.92 |
| CHEMBL5437384 | — | — | 1 | 7.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5420328 | — | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL5411543 | — | IC50 | = | 0.45 | nM | 9.35 |
| CHEMBL5407224 | — | IC50 | = | 0.81 | nM | 9.09 |
| CHEMBL486232 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL5437384 | — | IC50 | = | 64.0 | nM | 7.19 |