Assay Detail
Binding
CHEMBL5326422
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Inhibition of Plasmodium falciparum trophozite extracts FP-2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Falcipains: Biochemistry, target validation and structure-activity relationship studies of inhibitors as antimalarials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.11 | 9.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5437384 | — | — | 1 | 9.44 |
| CHEMBL5398692 | — | — | 1 | 9.38 |
| CHEMBL5407224 | — | — | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5437384 | — | IC50 | = | 0.36 | nM | 9.44 |
| CHEMBL5398692 | — | IC50 | = | 0.42 | nM | 9.38 |
| CHEMBL5407224 | — | IC50 | = | 3.0 | nM | 8.52 |