Assay Detail

CHEMBL5326425

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Functional

Antiplasmodial activity against Plasmodium vinckei

ChEMBL ↗

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Target

Plasmodium vinckei (CHEMBL4523073) ↗

Open DB target context

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Plasmodium vinckei (CHEMBL4523073) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Plasmodium vinckei

CHEMBL4523073

Anchored from Assay target.

Protein identity Plasmodium vinckei

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Plasmodium vinckei
Confidence	1 — Organism
Curated By	Autocuration

Target

Plasmodium vinckei (CHEMBL4523073) ↗

Type	ORGANISM
Organism	Plasmodium vinckei

Publication

Falcipains: Biochemistry, target validation and structure-activity relationship studies of inhibitors as antimalarials.

Patra J, Rana D, Arora S, Pal M, Mahindroo N.
Eur J Med Chem (2023) 252 : 115299 -115299
PubMed 36996716 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.70	8.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL486232	—	—	1	8.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL486232	—	IC50	=	2.0	nM	8.70