Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5326934

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human LX2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type LX-2
Confidence 1 — Organism
Curated By Autocuration

Target

LX-2 (CHEMBL5465457)
Type CELL-LINE
Organism Homo sapiens

Publication

Design, synthesis and biological evaluation of matrine-dithiocarbamate hybrids as potential anticancer agents.
Zhang MW, He Y, Wei MX.
Eur J Med Chem (2023) 254 : 115375 -115375
PubMed 37084600 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.02 4.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5423476 1 4.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5423476 IC50 = 96330.0 nM 4.02