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Assay Detail

CHEMBL5327312

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to fluorescently labeled Cdc42 (unknown origin) assessed as dissociation constant by microscale thermophoresis assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cell division control protein 42 homolog (CHEMBL6088)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Advances in the development of Rho GTPase inhibitors.
Zhang Y, Li G, Zhao Y.
Bioorg Med Chem (2023) 90 : 117337 -117337
PubMed 37253305 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.48 6.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4303199 1 6.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4303199 Kd = 332.0 nM 6.48