Assay Detail
Binding
CHEMBL5327313
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GST-tagged wildtype Cdc42 (unknown origin) incubated for 2 hrs in presence of BODIPY FL GTP by flow cytometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Cell division control protein 42 homolog (CHEMBL6088) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Advances in the development of Rho GTPase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.68 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1370630 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1370630 | — | EC50 | = | 2100.0 | nM | 5.68 |