Assay Detail
Binding
CHEMBL5327985
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Binding affinity to mouse TYK2 JH2 domain assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Non-receptor tyrosine-protein kinase TYK2 (CHEMBL2321619) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 10.17 | 10.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5422616 | — | — | 1 | 10.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5422616 | — | Kd | = | 0.067 | nM | 10.17 |