Assay Detail
Binding
CHEMBL5328512
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GSK-3beta (unknown origin) expressed in Sf21 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf21 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Glycogen synthase kinase-3: A potential target for diabetes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.96 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50894 | ALSTERPAULLONE | — | 1 | 8.40 |
| CHEMBL388978 | STAUROSPORINE | — | 1 | 7.82 |
| CHEMBL216543 | — | — | 1 | 7.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50894 | ALSTERPAULLONE | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL388978 | STAUROSPORINE | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL216543 | — | IC50 | = | 22.0 | nM | 7.66 |