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Assay Detail

CHEMBL5328513

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human full length GSK-3 beta transfected in Sf21 cells assessed as inhibition constant measured after 6 hrs by scintillation method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type Sf21
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glycogen synthase kinase-3 beta (CHEMBL262)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Glycogen synthase kinase-3: A potential target for diabetes.
Teli DM, Gajjar AK.
Bioorg Med Chem (2023) 92 : 117406 -117406
PubMed 37536264 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.42 7.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259850 1 7.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259850 Ki = 38.0 nM 7.42