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Assay Detail

CHEMBL5328521

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Neuroprotective activity against CORT-induced damage in rat PC-12 cells measured after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Cell Type PC-12
Confidence 1 — Organism
Curated By Autocuration

Target

PC-12 (CHEMBL612556)
Type CELL-LINE
Organism Rattus norvegicus

Publication

Glycogen synthase kinase-3: A potential target for diabetes.
Teli DM, Gajjar AK.
Bioorg Med Chem (2023) 92 : 117406 -117406
PubMed 37536264 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5400226 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5400226 EC50 = 3.0 nM 8.52