Assay Detail
Binding
CHEMBL5328661
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Binding affinity to human partial length BRD9 bromodomain (130 to 259 residues) expressed in bacterial expression system by BROMOscan KdELECT analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.19 | 6.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5413197 | — | — | 1 | 6.19 |
| CHEMBL5412877 | — | — | 1 | 6.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5413197 | — | Kd | = | 650.0 | nM | 6.19 |
| CHEMBL5412877 | — | Kd | = | 655.0 | nM | 6.18 |