Assay Detail
Binding
CHEMBL5328665
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of NanoBRET BRD Tracer-02 from Nanoluc-fused BRD9 bromodomain (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRET assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.20 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3823478 | — | — | 1 | 7.62 |
| CHEMBL5412877 | — | — | 1 | 5.50 |
| CHEMBL5413197 | — | — | 1 | 5.48 |
| CHEMBL1522313 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3823478 | — | IC50 | = | 24.0 | nM | 7.62 |
| CHEMBL5412877 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL5413197 | — | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL1522313 | — | IC50 | - | — | - |