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Assay Detail

CHEMBL5328985

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human Lung cancer cell line assessed as inhibition of cell growth measured at 72 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Lung cancer cell line
Confidence 1 — Organism
Curated By Autocuration

Target

Lung cancer cell line (CHEMBL614790)
Type CELL-LINE
Organism Homo sapiens

Publication

Pyrrolidinedione-thiazolidinone hybrid molecules with potent cytotoxic effect in squamous cell carcinoma SCC-15 cells.
Finiuk N, Kaleniuk E, Holota S, Stoika R, Lesyk R, Szychowski KA.
Bioorg Med Chem (2023) 92 : 117442 -117442
PubMed 37579525 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5190672 1 6.00
CHEMBL5200894 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5190672 IC50 = 1000.0 nM 6.00
CHEMBL5200894 IC50 = 1000.0 nM 6.00