Assay Detail
Functional
CHEMBL5328987
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Cytotoxicity against human SCC-15 cells assessed as LDH release incubated for 24 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SCC-15 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pyrrolidinedione-thiazolidinone hybrid molecules with potent cytotoxic effect in squamous cell carcinoma SCC-15 cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.75 | 4.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5200894 | — | — | 1 | 4.83 |
| CHEMBL5428617 | — | — | 1 | 4.81 |
| CHEMBL5190672 | — | — | 1 | 4.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5200894 | — | EC50 | = | 14820.0 | nM | 4.83 |
| CHEMBL5428617 | — | EC50 | = | 15390.0 | nM | 4.81 |
| CHEMBL5190672 | — | EC50 | = | 24850.0 | nM | 4.61 |