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Assay Detail

CHEMBL5329013

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against mouse BALB/3T3 cells assessed reduction in cellular metabolic activity incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Mus musculus
Cell Type BALB/3T3
Confidence 1 — Organism
Curated By Autocuration

Target

BALB/3T3 (CHEMBL613876)
Type CELL-LINE
Organism Mus musculus

Publication

Pyrrolidinedione-thiazolidinone hybrid molecules with potent cytotoxic effect in squamous cell carcinoma SCC-15 cells.
Finiuk N, Kaleniuk E, Holota S, Stoika R, Lesyk R, Szychowski KA.
Bioorg Med Chem (2023) 92 : 117442 -117442
PubMed 37579525 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.07 4.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5428617 1 4.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5428617 IC50 = 85180.0 nM 4.07