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Assay Detail

CHEMBL5329399

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against Chloroquine resistant Plasmodium falciparum Dd2 assessed as parasitic growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Is structural hybridization invoking new dimensions for antimalarial drug discovery research?
Sharma B, Agarwal A, Awasthi SK.
RSC Med Chem (2023) 14 : 1227 -1253
PubMed 37484560 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.88 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL209953 1 8.30
CHEMBL76 CHLOROQUINE 4.0 1 7.45

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL209953 IC50 = 5.0 nM 8.30
CHEMBL76 CHLOROQUINE IC50 = 35.13 nM 7.45