Assay Detail
Functional
CHEMBL5329404
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Antimalarial activity against Chloroquine sensitive Plasmodium falciparum 3D7 assessed as parasitic growth inhibition measured after 3 days by ELISA assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Is structural hybridization invoking new dimensions for antimalarial drug discovery research?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.79 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 8.70 |
| CHEMBL5177798 | — | — | 1 | 6.40 |
| CHEMBL5404285 | — | — | 1 | 6.22 |
| CHEMBL506 | PRIMAQUINE | 4.0 | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL5177798 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL5404285 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL506 | PRIMAQUINE | IC50 | = | 1500.0 | nM | 5.82 |