Assay Detail

CHEMBL5330347

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of Bordetella pertussis Adenylate cyclase toxin

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Bordetella pertussis
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Harvesting phosphorus-containing moieties for their antibacterial effects.

Voráčová M, Zore M, Yli-Kauhaluoma J, Kiuru P.
Bioorg Med Chem (2023) 96 : 117512 -117512
PubMed 37939493 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	7.30	7.75

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1162433	ADEFOVIR DIPHOSPHATE	-1.0	1	7.75
CHEMBL5395148	—	—	1	6.84

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1162433	ADEFOVIR DIPHOSPHATE	IC50	=	18.0	nM	7.75
CHEMBL5395148	—	IC50	=	145.0	nM	6.84