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Assay Detail

CHEMBL5331173

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

A comprehensive review on acridone based derivatives as future anti-cancer agents and their structure activity relationships.
Yadav TT, Murahari M, Peters GJ, Yc M.
Eur J Med Chem (2022) 239 : 114527 -114527
PubMed 35717872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.74 5.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL349609 ARBORININE 1 5.74

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL349609 ARBORININE IC50 = 1840.0 nM 5.74