Assay Detail
Functional
CHEMBL5331177
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by alamar blue reagent based fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A comprehensive review on acridone based derivatives as future anti-cancer agents and their structure activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.66 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5435858 | — | — | 1 | 6.66 |
| CHEMBL451705 | CITRUSININE-I | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5435858 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL451705 | CITRUSININE-I | IC50 | = | 220.0 | nM | 6.66 |