Assay Detail
Binding
CHEMBL5331192
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of telomerase (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A comprehensive review on acridone based derivatives as future anti-cancer agents and their structure activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.04 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL186346 | — | — | 1 | 6.70 |
| CHEMBL365070 | — | — | 1 | 5.77 |
| CHEMBL365069 | — | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL186346 | — | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL365070 | — | EC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL365069 | — | EC50 | = | 2300.0 | nM | 5.64 |