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Assay Detail

CHEMBL5331197

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MCF7/Mitox cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7/Mitox
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A comprehensive review on acridone based derivatives as future anti-cancer agents and their structure activity relationships.
Yadav TT, Murahari M, Peters GJ, Yc M.
Eur J Med Chem (2022) 239 : 114527 -114527
PubMed 35717872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.24 5.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5408450 1 5.29
CHEMBL5421998 1 5.29
CHEMBL509779 1 5.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5408450 IC50 = 5100.0 nM 5.29
CHEMBL5421998 IC50 = 5100.0 nM 5.29
CHEMBL509779 IC50 = 7400.0 nM 5.13