Assay Detail
Binding
CHEMBL5331241
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Inhibition of VIM2 (unknown origin)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent advances in β-lactamase inhibitor chemotypes and inhibition modes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.16 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5415874 | — | — | 1 | 7.70 |
| CHEMBL4177035 | — | — | 1 | 7.26 |
| CHEMBL434965 | D-CAPTOPRIL | — | 1 | 7.14 |
| CHEMBL4169182 | — | — | 1 | 5.97 |
| CHEMBL1560 | CAPTOPRIL | 4.0 | 1 | 5.36 |
| CHEMBL4087144 | — | — | 1 | 4.97 |
| CHEMBL3577963 | — | — | 1 | 4.70 |
| CHEMBL4217706 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5415874 | — | IC50 | = | 19.95 | nM | 7.70 |
| CHEMBL4177035 | — | IC50 | = | 55.0 | nM | 7.26 |
| CHEMBL434965 | D-CAPTOPRIL | IC50 | = | 72.0 | nM | 7.14 |
| CHEMBL4169182 | — | IC50 | = | 1060.0 | nM | 5.97 |
| CHEMBL1560 | CAPTOPRIL | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL4087144 | — | IC50 | = | 10800.0 | nM | 4.97 |
| CHEMBL3577963 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL4217706 | — | IC50 | > | 400000.0 | nM | - |