Assay Detail
Binding
CHEMBL5331244
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Inhibition of BCl1 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent advances in β-lactamase inhibitor chemotypes and inhibition modes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.84 | 5.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4177035 | — | — | 1 | 5.79 |
| CHEMBL434965 | D-CAPTOPRIL | — | 1 | 4.97 |
| CHEMBL4169182 | — | — | 1 | 4.52 |
| CHEMBL1560 | CAPTOPRIL | 4.0 | 1 | 4.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4177035 | — | IC50 | = | 1630.0 | nM | 5.79 |
| CHEMBL434965 | D-CAPTOPRIL | IC50 | = | 10700.0 | nM | 4.97 |
| CHEMBL4169182 | — | IC50 | = | 30400.0 | nM | 4.52 |
| CHEMBL1560 | CAPTOPRIL | IC50 | = | 80400.0 | nM | 4.09 |