Assay Detail
Binding
CHEMBL5331250
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Inhibition of VIM1 (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances in β-lactamase inhibitor chemotypes and inhibition modes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.16 | 9.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5404362 | — | — | 1 | 9.90 |
| CHEMBL5408399 | — | — | 1 | 9.58 |
| CHEMBL5428850 | — | — | 1 | 8.00 |
| CHEMBL5415874 | — | — | 1 | 6.90 |
| CHEMBL4177035 | — | — | 1 | 6.28 |
| CHEMBL4217706 | — | — | 1 | 4.97 |
| CHEMBL4169182 | — | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5404362 | — | IC50 | = | 0.125 | nM | 9.90 |
| CHEMBL5408399 | — | IC50 | = | 0.264 | nM | 9.58 |
| CHEMBL5428850 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5415874 | — | IC50 | = | 125.89 | nM | 6.90 |
| CHEMBL4177035 | — | IC50 | = | 526.0 | nM | 6.28 |
| CHEMBL4217706 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL4169182 | — | IC50 | = | 33730.0 | nM | 4.47 |