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Assay Detail

CHEMBL5331343

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Escherichia coli CTX-M-15 assessed as inhibition constant using nitrocefin as substrate by microplate reader analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Recent advances in β-lactamase inhibitor chemotypes and inhibition modes.
Li R, Chen X, Zhou C, Dai QQ, Yang L.
Eur J Med Chem (2022) 242 : 114677 -114677
PubMed 35988449 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2031559 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2031559 Ki = 250.0 nM 6.60