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Assay Detail

CHEMBL5331469

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against influenza A virus H5N1 infected in dog MDCK cells assessed as viral growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

The current strategies of optimization of oseltamivir against mutant neuraminidases of influenza A:A review.
Wang K, Zhang H, Tian Y.
Eur J Med Chem (2022) 243 : 114711 -114711
PubMed 36055001 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.09 6.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5416900 1 6.54
CHEMBL5417759 1 5.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5416900 EC50 = 290.0 nM 6.54
CHEMBL5417759 EC50 = 2300.0 nM 5.64