Assay Detail
Binding
CHEMBL5331470
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of influenza A virus H5N1 Neuraminidase H274Y mutant in dog MDCK cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza A virus |
| Cell Type | MDCK |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The current strategies of optimization of oseltamivir against mutant neuraminidases of influenza A：A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.61 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5416900 | — | — | 1 | 6.96 |
| CHEMBL5417759 | — | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5416900 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL5417759 | — | EC50 | = | 56000.0 | nM | 4.25 |