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Assay Detail

CHEMBL5331484

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist activity at 125I-labeled CCK-33 in rat pancreas
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Pancreas
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cholecystokinin (CHEMBL5465544)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Recent progress toward developing axial chirality bioactive compounds.
Wang Z, Meng L, Liu X, Zhang L, Yu Z, Wu G.
Eur J Med Chem (2022) 243 : 114700 -114700
PubMed 36058089 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.85 5.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL283117 ASPERLICIN 1 5.85
CHEMBL316561 PROGLUMIDE 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL283117 ASPERLICIN IC50 = 1400.0 nM 5.85
CHEMBL316561 PROGLUMIDE IC50 = 600000.0 nM -