Assay Detail
Binding
CHEMBL5331919
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HIV-1 integrase strand transfer activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 integrase (CHEMBL3471) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Current medicinal chemistry strategies in the discovery of novel HIV-1 ribonuclease H inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.66 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4865520 | — | — | 1 | 5.30 |
| CHEMBL45578 | — | — | 1 | 4.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4865520 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL45578 | — | IC50 | = | 98000.0 | nM | 4.01 |