Assay Detail
Functional
CHEMBL5332007
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HCMV infected in human NHDF cells assessed as reduction in virus plaque formation
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.35 | 8.35 |
| EC90 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1241951 | LETERMOVIR | 4.0 | 2 | 8.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1241951 | LETERMOVIR | EC50 | = | 4.5 | nM | 8.35 |
| CHEMBL1241951 | LETERMOVIR | EC90 | = | 6.1 | nM | - |