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Assay Detail

CHEMBL5332011

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Variola virus assessed as reduction in virus-induced cytopathic effect
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Variola virus
Confidence 1 — Organism
Curated By Autocuration

Target

Variola virus (CHEMBL613494)
Type ORGANISM
Organism Variola virus

Publication

A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives.
Gu J, Wu Q, Zhang Q, You Q, Wang L.
Eur J Med Chem (2022) 243 : 114742 -114742
PubMed 36155354 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1257073 TECOVIRIMAT 4.0 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1257073 TECOVIRIMAT EC50 = 40.0 nM 7.40