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Assay Detail

CHEMBL5332083

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Toxicity
Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type L02
Confidence 1 — Organism
Curated By Autocuration

Target

L02 (CHEMBL4296457)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of a novel piperlongumine analogue as a microtubule polymerization inhibitor with potent anti-angiogenic and anti-metastatic efficacy.
Qin J, Li H, Wang X, Zhang Y, Duan Y, Yao Y, Yang H, Sun M.
Eur J Med Chem (2022) 243 : 114738 -114738
PubMed 36162214 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.64 4.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5419960 1 4.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5419960 IC50 = 22740.0 nM 4.64