Assay Detail
Functional
CHEMBL5332158
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Antiproliferative activity against human A549 cells assessed as inhibition of cell growth
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bisindole natural products: A vital source for the development of new anticancer drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.67 | 8.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5430259 | — | — | 1 | 8.51 |
| CHEMBL506768 | CONOPHYLLINE | — | 1 | 6.77 |
| CHEMBL5398385 | — | — | 1 | 6.77 |
| CHEMBL5424676 | — | — | 1 | 5.89 |
| CHEMBL5406271 | — | — | 1 | 5.42 |
| CHEMBL302882 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5430259 | — | IC50 | = | 3.09 | nM | 8.51 |
| CHEMBL506768 | CONOPHYLLINE | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL5398385 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL5424676 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL5406271 | — | IC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL302882 | — | IC50 | = | 1.0 | ug.mL-1 | - |